I'm about to run plastic fuel hose, it's DIN 73378 certified for automotive fuel use. It's pressure rated to 100bar so assume that's enough for a multipoint EFI system. But the working temperature rating is only 80 Celsius.

Can I run this all the way to my engine or will it be over 80 C in the engine bay, on the opposite side away from the exhaust.

A hot engine will exceed 105 degree's, I would terminate on your bulkhead and extend out with flexible fuel hose.